Uppercase, one left margin, no commas
Section 212 is short and blunt: "Format all lines of the address with a uniform left margin. Uppercase letters are preferred on all lines of the address block." Lowercase in various type styles is acceptable when it meets the readability guidance for automation. Section 222 removes the punctuation, keeping only the hyphen inside a ZIP+4, and section 224 asks for at least one space between city, state abbreviation and code, with two preferred before the code.
The delivery line is a set of fields
Section 231 lists what the line breaks down into: the primary address number, predirectional, street name, suffix, postdirectional, secondary address identifier and secondary address, with one space between elements. It also describes how the Postal Service reads it, starting "from the right-most element of the address and work toward the left" until every component is isolated. Section 234.2 handles the awkward case of two consecutive suffix words by abbreviating the second and spelling the first out as part of the street name.
Attention lines, firms and the recipient
Section 214 puts the attention line "above the Recipient Line, that is, above the name of the firm to which the mailpiece is directed", which is the reverse of how most people type it. For a business shipment that means the person goes on top and the company underneath, then the street. All of the above is from pe.usps.com, checked 2026-07-28.